TI utilizes an approach of modeling, measurement, and implementation to develop and validate ways to make complex information systems trustworthy. Its goals are to establish fundamental and enabling science and technology for building trustworthy information systems, to develop techniques for assessing trustworthiness of information systems, and to apply the developed techniques to critical applications, including those in aerospace systems, power systems, data & information processing systems, transportation systems, emergency response systems, and e-commerce and financial systems.

Research themes include Power Grid, Health Information, Systems & Networking, Evaluation, and Data Science.